Biochemistry

John T. Tansey 저자(글)

WILEY · 2022년 07월 01일

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작가정보

저자(글) John T. Tansey

목차

• 1 The Chemical Foundations of Biochemistry
  Chemistry in Context
  1.1 General Chemical Principles
  1.2 Fundamental Concepts of Organic Chemistry
  1.3 The Chemistry of Water
  
  2 Nucleic Acids
  Nucleic Acids in Context
  Nucleic acids are the Genetic Materials
  2.1 Nucleic Acids Have Distinct Structures
  2.2 Nucleic Acids Have Many Cellular Functions
  2.3 The Manipulation of Nucleic Acids Has Transformed Biochemistry
  
  3 Proteins I: An Introduction to Protein Structure, Function, and its Purification
  Proteins in Context
  3.1 Amino Acid Chemistry
  3.2 Proteins Are Polymers of Amino Acids
  3.3 Proteins Are Molecules of Defined Shape and Structure
  3.4 Examples of Protein Structures and Functions
  3.5 Protein Purification Basics
  3.6 Size-Exclusion Chromatography
  3.7 Affinity Chromatography
  
  4 Proteins II: Enzymes
  Enzymes in Context
  4.1 Introduction to Enzymes
  4.2 Enzymes Increase Reaction Rate
  4.3 The Mechanism of an Enzyme Can Be Deduced from Structural, Kinetic, and Spectral Data
  4.4 Examples of Enzyme Regulation
  4.5 Allosterism and Cooperativity
  4.6 Hemoglobin
  4.7 Receptor?Ligand Interactions
  
  5 Membranes and an Introduction to Signal Transduction
  Biochemistry in Context
  5.1 Membrane Structure and Function
  5.2 Signal Transduction
  
  6 Carbohydrates I: Mono- and Disaccharides, Glycolysis, Gluconeogenesis, and the Fates of Pyruvate
  Carbohydrates in Context
  6.1 Properties, Nomenclature, and Biological Functions of Monosaccharides
  6.2 Properties, Nomenclature, and Biological Functions of Complex Carbohydrates
  6.3 Glycolysis and an Introduction to Metabolic Pathways
  6.4 Gluconeogenesis
  6.5 The Fates of Pyruvate
  
  7 The Common Catabolic Pathway: Citric Acid Cycle, the Electron Transport Chain, and ATP Biosynthesis
  Electron Transport in Context
  7.1 The Citric Acid Cycle
  7.2 The Electron Transport Chain
  7.3 ATP Biosynthesis
  
  8 Carbohydrates II: Glycogen Metabolism, the Pentose Phosphate Pathway, Glycoconjugates, and Extracellular Matrices
  Polysaccharides in Context
  8.1 Glycogen Metabolism
  8.2 The Pentose Phosphate Pathway
  8.3 Carbohydrates in Glycoconjugates
  8.4 Extracellular Matrices and Biofilms
  
  9 Lipids I: Fatty Acids, Steroids, and Eicosanoids; Beta-Oxidation and Fatty Acid Biosynthesis
  Lipids in Context
  9.1 Properties, Nomenclature, and Biological Functions of Lipid Molecules
  9.2 Fatty Acid Biosynthesis
  9.3 Fatty Acid Catabolism
  9.4 Ketone Body Metabolism
  9.5 Steroid Metabolism
  9.6 Eicosanoid and Endocannabinoid Metabolism
  
  10 Lipids II: Metabolism and Transport of Complex Lipids
  Complex Lipids in Context
  10.1 Phospholipid Metabolism
  10.2 Digestion of Triacylglycerols
  10.3 Transport of Lipids in the Circulation
  10.4 Entry of Lipids into the Cell
  10.5 Neutral Lipid Biosynthesis
  10.6 Lipid Storage Droplets, Fat Storage, and Mobilization
  10.7 Lipid Rafts as a Biochemical Entity
  
  11 Amino Acid and Amine Metabolism
  Amine Metabolism in Context
  11.1 Digestion of Proteins
  11.2 Amino Acid Deamination and Transamination
  11.3 The Urea Cycle
  11.4 Metabolism of Amino Acid Carbon Skeleton
  11.5 The Detoxification of Other Amines and Xenobiotics
  11.6 The Biochemistry of Renal Function
  
  12 Regulation and Integration of Metabolism
  Metabolism in Context
  12.1 A Review of the Pathways and Crossroads of Metabolism
  12.2 Organ Specialization and Metabolic States
  12.3 Communication between Organs
  12.4 Metabolic Disease
  
  13 Nucleotide and Deoxynucleotide Metabolism
  Nucleotides and Deoxynucleotides in Context
  13.1 Purine Biosynthesis
  13.2 Pyrimidine Biosynthesis
  13.3 Deoxyribonucleotide Biosynthesis
  13.4 Catabolism of Nucleotides
  
  14 DNA Replication, Damage, and Repair
  DNA in Context
  14.1 Challenges of DNA Replication
  14.2 DNA Replication in Prokaryotes
  14.3 DNA Replication in Eukaryotes
  14.4 DNA Damage and Repair
  14.5 Homologous Recombination
  
  15 RNA Synthesis and Processing
  RNA Synthesis in Context
  15.1 Transcription: RNA Synthesis
  15.2 Processing of Nascent Eukaryotic RNA Messages
  15.3 RNA Export from the Nucleus
  
  16 Protein Biosynthesis
  Protein Synthesis in Context
  16.1 The Genetic Code
  16.2 Machinery Involved in in Protein Biosynthesis
  16.3 Mechanism of Protein Biosynthesis
  
  17 Control and Regulation of Gene Expression
  Gene Regulation in Context
  17.1 DNA--Protein Interactions
  17.2 Regulation of Gene Expression in Prokaryotes
  17.3 Regulation of Gene Expression in Eukaryotes
  
  18 Determination of Macromolecular Structure
  Macromolecular Structure in Context
  18.1 An Introduction to Structure Determination
  18.2 Electron Microscopy?Types and Advantages
  18.3 X-Ray Diffraction and Neutron Scattering
  18.4 Nuclear Magnetic Resonance
  
  19 Protein Production, Engineering and Folding
  Protein Production, Engineering and Folding in Context
  19.1 Protein Production
  19.2 Protein Engineering
  19.3 Protein Folding
  
  20 Bioinformatics and Omics
  Bioinformatics in Context
  20.1 Introduction to Bioinformatics
  20.2 Generating Bioinformatic Data
  20.3 Analyzing Bioinformatic Data
  
  21 Signal Transduction
  Cell Signaling in Context
  21.1 A Review of Signal Transduction
  21.2 An Overview of Regulation of Signal Transduction
  21.3 Six New Signal Transduction Pathways
  
  22 Protein Trafficking
  Protein Trafficking in Context
  22.1 Molecular Aspects of Protein Trafficking
  22.2 Molecular Motor Proteins
  22.3 Vesicular Fusion
  
  
  23 Photosynthesis and Nitrogen Fixation
  Photosynthesis and Nitrogen Fixation in Context
  23.1 Photosynthesis
  23.2 Nitrogen Fixation
  
  Techniques
  
  Solutions
  
  Glossary
  
  Index

기본정보

ISBN	9781119820802 ( 1119820804 )
발행(출시)일자	2022년 07월 01일
쪽수	880쪽
크기	217 * 276 * 40 mm / 2297 g
총권수	1권
언어	영어